Mass Spectrometry

DLS Solutions Applications : Mass Spectrometry

Mass Spectrometry systems can be used to determine the elemental composition of a sample or molecule. MS can also determine the chemical structures of molecules and produce accurate mass determinations. The MS analytical technique typically begins by ionizing chemical compounds to generate charged molecules or molecular fragments. The spectrometer then measures the mass-to-charge (m/z) ratios of these fragments by subjecting them to an electric and/or magnetic field and determining the abundances of each ion present.

The technique has both qualitative and quantitative uses. These include identifying unknown compounds, determining the isotopic composition of elements in a molecule, and determining the structure of a compound by observing its fragmentation. Other uses include quantifying the amount of a compound in a sample, studying the fundamentals of gas phase ion chemistry, and studying physical, chemical, and/or biological properties of compounds.

Typically, MS analyzer systems are Quadrupole, Triple Quadrupole, or Time of Flight, and may come with optional accessories, such as ion trap assemblies, MALDI imaging sample introduction, and autosampler introduction. MS systems are also often used in tandem with Liquid Chromatography or Gas Chromatography systems.

Mass Spectrometry is used in laboratory applications such as Proteomics, Protein and Peptide analysis, Isotope ratio and Accurate Mass determination, Trace gas analysis,Pharmacokinetics.